WebUltra-fine anaphase DNA bridges (UFBs) were discovered in our group over 10 years ago. They are nucleosome-free DNA threads that connect the separating sister DNA masses … Web21 Mar 2024 · If not timely processed, these DNA joint molecules can give rise to the so-called ultrafine anaphase bridges (UFBs), which are fine DNA threads that cannot be …
Bloom’s Syndrome and PICH Helicases Cooperate with ... - PLOS
WebFailure to properly disentangle catenated sister chromatids can lead to the formation of bulky or ultrafine anaphase bridges, and ultimately genome instability. In this review we present an overview of the current state of knowledge of how sister chromatid decatenation is carried out, with particular focus on the role of TOP2A and TOPBP1 in this process. Web20 Sep 2024 · FX cells treated with 5-fluoro-2′-deoxyuridine (FdU), a direct inhibitor of thymidylate synthase, show an increase not only in the expression of the fragile site, but … david ortiz\\u0027s 1 768 briefly crossword clue
A new class of ultrafine anaphase bridges generated by …
Webstructure-specific nuclease; ultrafine anaphase bridge; chromosome segregation; mitotic DNA synthesis; genome stability 1. Introduction DNA replication requires the unwinding of the parental DNA duplex by the replicative helicase, which leads to the formation of branched DNA structures that are known as replication forks (RFs). Web1 Jan 2024 · Ultrafine anaphase bridges (UFBs) are thin DNA threads linking the separating sister chromatids in the anaphase of mitosis. UFBs are thought to form when topological … http://sro.sussex.ac.uk/id/eprint/82640/1/genes-10-00232.pdf david ortiz\u0027s 1 768 briefly crossword clue