Pttg1 transcription factor
WebAug 16, 2013 · The aberrant expression of proto-oncogenes is involved in processes that are responsible for cellular proliferation and the inhibition of myeloid differentiation in acute … WebOct 30, 2024 · Transcription factor SP1 was up-regulated in PDGF-BB-stimulated HAVSMCs, combined with PTTG1 promoter sequence and regulated PTTG1 expression, whose overexpression reversed the effects of PTTG1 interference on cell proliferation, migration and phenotypic switching. SP1 transcriptional activation of PTTG1 activated MAPK/ERK …
Pttg1 transcription factor
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WebChromatin immunoprecipitation-on-chip study reveals that PTTG1 is a global transcription factor, which exerts its transcriptional activity either by directly binding to DNA or by … WebOct 30, 2024 · PTTG1 is also one of the inductive factors for the upregulated expression of pro-inflammatory TNF-α and oncogenic c-myc as well as the aggravated cell proliferation …
WebDec 24, 2024 · The effect of ECT2 on the stability of E2F transcription factor 1 (E2F1) and the expression of PTTG1 were examined by western blot, co-immunoprecipitation, and in vivo ubiquitination assays. Results ECT2 was upregulated in gliomas and was negatively correlated with prognosis; its downregulation inhibited glioma cell proliferation. WebJan 22, 2024 · Esophageal squamous cell carcinoma (ESCC) is the major histological type of esophageal cancers worldwide. Transcription factor PTTG1 was seen highly expressed in …
WebInterestingly, transcription factors were significantly underrepresented among the differentially expressed genes, and only one transcription factor, Pttg1, showed significant differences between ... WebNov 21, 2012 · Human pituitary tumor transforming gene-1 (PTTG1) is a novel oncogene. Its overexpression occurs in a wide variety of human tumors including pituitary adenomas. …
WebPTTG1 has transcriptional activity and exerts its function either by directly binding to DNA or by interacting with other proteins such as other transcription factors [13]. PTTG1 overexpression ...
WebJul 28, 2024 · Overall, our findings indicate that PTTG1 is a glioma malignant factor that promotes angiogenesis, migration, invasion, and the evasion of apoptosis, and these roles … ting apple watch cellularWebFIGURE 5 PTTG1 induces EMT via AKT signaling and Snail in breast cancer cells. A and B, transfection with siRNA targeting PTTG1 increased epithelial marker, E-cadherin, and decreased transcription factor Snail and mesenchymal markers, N-cadherin and vimentin in BT549 (A) and MDA-MB-231 (B), that express high levels of PTTG1. Detection of E ... party yacht rentals los angelesWebJun 1, 2012 · Because ectopic expression of PTTG1 in normal breast MCF10A cells led to AKT activation, induction of transcription factor Snail, and acquisition of migratory and invasive properties, we next examined whether down-regulation of PTTG1 attenuates mesenchymal properties and thereby suppresses migration and invasiveness in breast … tinga nursery wilmington ncWebJun 29, 2024 · Pituitary tumor transforming gene-1 (PTTG1) transcription factor is identified as carcinogenic and associated with tumor invasiveness, but its role in bladder cancer … partyyards.funWebOct 30, 2024 · PTTG1 is also one of the inductive factors for the upregulated expression of pro-inflammatory TNF-α and oncogenic c-myc as well as the aggravated cell proliferation in hepatocellular carcinoma [9]. ... The promoter selective transcription factor SP1 regulates the expression of multiple genes and is involved in many cellular processes including ... tinga nursery wilmington north carolinaWebMar 27, 2024 · Keratinocyte growth factor (KGF) is a potent mitogen for epithelial cells, and it promotes survival of these cells under stress conditions. In a search for KGF-regulated … tinga nursery - castle hayneWebThe encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) … party yacht rental orlando