2024 Harlan sprague dawley rats

Harlan sprague dawley rats

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August undefined, 2024

WebAug 9, 2024 · Morphological Features. Morphologically Sprague Dawley rat has a long narrow head along with a tail length higher than its own body and a little higher than the Wistar rat. 2. High Reproductive Rate. Their age … A "strain", in reference to rodents, is a group in which all members are, as nearly as possible, genetically identical. In rats, this is accomplished through inbreeding. By having this kind of population, it is possible to conduct experiments on the roles of genes, or conduct experiments that exclude variations in genetics as a factor. By contrast, "outbred" populations are used …

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WebThe original company continues today as Harlan Sprague–Dawley. A second business was established in the 1940s by Evan Carl Holzman using Sprague–Dawley rats from the original colony. ... As with the Wistar strains, the use of the Sprague–Dawley rat strain has been criticized as being an outbred strain, of variable, and essentially ... WebJul 6, 2024 · Author Summary Outbred Sprague Dawley rats are among the most commonly used rats for neuroscience, physiology and pharmacological research; in the year 2024, 4,188 publications contained the keyword “Sprague Dawley”. Rats identified as “Sprague Dawley” are sold by several commercial vendors, including Charles River … government printing press borella

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WebOur IACUC reviewed and approved all animal protocols. We obtained timed pregnant Holtzman rats from Harlan Sprague Dawley, Inc. (Indianapolis, IN). These rats have a gestation period of 22 d. WebThe first Sprague Dawley ® rat colony began in 1925, when Robert Dawley developed a vigorous rat with a good temperament and high rates of lactation. These rats were eventually used to study contraceptives. In 1980, the original colony was acquired by Harlan (now Inotiv). These albino rats are now used widely in medical and psychological research. WebArticle Title: Failure to respond to endogenous or exogenous melatonin may cause nonphotoresponsiveness in Harlan Sprague Dawley rats. doi: 10.1186/1740-3391-3-12. Figure Lengend Snippet: 24-hour urinary 6-sulfatoxymelatonin excretion rhythms (ng/2 h) for F344 and HSD rats in SD (upper panel) and LD (lower panel) . Values shown are means … government printing press chhattisgarh

Retracting Inconclusive Research: Lessons from the Séralini

WebJan 1, 2024 · The National Toxicology Program, which has used the F344 rat for much of its history, has recently changed to the Harlan Sprague–Dawley rat as its standard rat strain. While the F344 rat has high incidences of interstitial cell tumors of the testis, pituitary tumors, mononuclear cell leukemia, and adrenal pheochromocytomas, the Sprague ... WebFemale Harlan Sprague-Dawley rats were exposed to 0-2.0 mg PFDA/kg by oral gavage daily for 28 d. Female B 6 C 3 F 1 /N mice were exposed once/week to 0-5.0 mg … childrens curtain fabric starsWebevaluation that included multiple 2-year rat bioassays to evaluate the relative chronic toxicity and carcinogenicity of DLCs, structurally related PCBs, and mixtures of these … government printing press mumbai

"WebApr 25, 2015 · The study randomly assigned 100 male and 100 female Sprague-Dawley rats to ten different groups, ... Sells, D. M., Jokinen, M. P., & Walker, N. J. (2005). Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program. Toxicologic Pathology, 33(4), … " - Harlan sprague dawley rats

Harlan sprague dawley rats

Retracting Inconclusive Research: Lessons from the Séralini

WebA quantity of twenty rats (ten males and ten females) was submitted for testing, strain identified as Line Sprague Dawley® (NTac:SD), age 7 weeks. Rats were received at RBU 3, Taconic Biotechnology, Albany NY …

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WebAug 9, 2024 · Morphological Features. Morphologically Sprague Dawley rat has a long narrow head along with a tail length higher than its own body and a little higher than the Wistar rat. 2. High Reproductive Rate. Their age for reproduction is 8-10 weeks with a bodyweight of 250-300 grams, and gestation length is 21-23 days. WebThe breeding facilities were purchased first by Gibco and then by Harlan (now Harlan Sprague Dawley) in January 1980. The average litter size of the Sprague Dawley rat is 10.5. The adult body weight is 250–300g for females, and 450–520g for males. The typical life span is 2.5–3.5 years. These rats typically have increased tail to body ...

WebNov 1, 2024 · This is important as there are documented differences in epilepsy susceptibility following SE in Sprague Dawley rats obtained from different vendors . Of the two kainate model sites, one obtained Sprague Dawley rats from Charles River, while the other site obtained their Sprague Dawley rats from Harlan. WebJul 15, 2024 · Disposition and metabolism of the bisphenol analogue, bisphenol S, in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans Toxicol Appl Pharmacol . 2024 Jul 15;351:32-45. doi: 10.1016/j.taap.2024.05.008.

WebThe Sprague Dawley is an outbred, multipurpose breed of albino rat used extensively in medical and nutritional research. Its main advantage is its calmness and ease of handling. This breed of rat was first produced by the Sprague Dawley farms (later to become the Sprague Dawley Animal Company) in Madison, Wisconsin, in 1925 WebThey were bred from 6 Harlan Sprague Dawley females and 3 male Harlan Dark Agouti males. The lab tek kept 6 groups of these rats. All were inbred for 40 generations that was group 1. They were then out crossed after …

WebOur IACUC reviewed and approved all animal protocols. We obtained timed pregnant Holtzman rats from Harlan Sprague Dawley, Inc. (Indianapolis, IN). These rats have a …

WebFeb 7, 2011 · Uterine squamous metaplasia was reported at a high incidence in Harlan SD rats with control values reported between 32.0% and 44.2%. 1,35,36 It was shown that SD strains show higher incidences of uterine squamous metaplasia 1 in contrast to Wistar rats. 12 The incidence of this lesion in RccHan:WIST rats was established at 0.08% among … government printing office servicesWebThe Respondents, Indiana Department of State Revenue and Commissioner John R. Gildea, in his official capacity (collectively the Department), move to dismiss the … childrens curtain pole finialsWebLitter average: 11.0. Most widely-used outbred rat in animal research. Origin: Established in 1925 by Robert Dawley, the original Sprague Dawley rat colony was obtained by Harlan in 1980 through the acquisition of … government printing press maltaWebSuch a database is lacking for Harlan Sprague-Dawley (SD) rats. The intention of this paper is to report spontaneous lesions observed in female vehicle control Harlan SD … government printing vacancies 2022WebRats: Harlan Sprague-Dawley; Dose: 38 dams/dose group; 0, 100, 300, or 1000 mg/kg/day. 14-Day (C00058D) Completed . Evaluation of Genotoxicity and Epigenetic Modification of Black Cohosh; Citation: Seo JE, Guo X, Petibone DM, Shelton SD, Chen Y, Li X, Tryndyak V, Smith-Roe SL, Witt KL, Mei N, Manjanatha MG. Mechanistic evaluation … childrens curtain fabricWebApr 3, 2024 · Rats: Harlan Sprague-Dawley; Dose: 0, 5, 10, 20 mg/kg/day. GD 6 to PND 120 F0 Generation (Gavage) (MOG10035B) Data in Review . Rats: Harlan Sprague … childrens curtains argosWebOct 12, 2024 · Wild type (WT) and RBM20 knockout (KO) rats used in this study were crosses of Sprague-Dawley (SD) × Brown Norway (BN). All strains were originally obtained from Harlan Sprague Dawley, Indianapolis, IN, USA. KO rats are derived from a spontaneous mutant. Animals were fed standard rodent chow. government printing press karnataka