WebAtorvastatin calcium USP is a synthetic lipid-lowering agent. Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin calcium USP is (βR,δR)-2- (p-fluorophenyl)-β,δ ... WebStatins include atorvastatin (Lipitor), fluvastatin (Lescol XL), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor, Ezallor) and simvastatin (Zocor, FloLipid). Having too much cholesterol in your blood increases your risk of heart attacks and strokes.
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WebJun 20, 2024 · Atorvastatin is a medication prescribed by a doctor to lower cholesterol in people who have been diagnosed with high cholesterol (high levels of cholesterol in the … WebSep 2, 2024 · Atorvastatin is highly plasma protein bound (over 98%) and has a volume of distribution of about 380 liters. Metabolism Atorvastatin is metabolized by cytochrome P450 3A4 (CYP3A4) to active ortho- and para-hydroxylated metabolites. Excretion Atorvastatin and its metabolites get eliminated in bile. digital technology and cyber services dps
Atorvastatin - Side Effects, Uses, Dosage, Overdose, Pregnancy …
WebApr 1, 2024 · Atorvastatin belongs to the group of medicines called HMG-CoA reductase inhibitors, or statins. It works by blocking an enzyme that is needed by the body to make cholesterol, and this reduces the amount of cholesterol in the blood. This medicine is available only with your doctor's prescription. WebAtorvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Brand Names Caduet, Lipitor, Lypqozet Generic Name Atorvastatin DrugBank Accession Number DB01076 Background WebIntroduction. Reduction of mortality and morbidity of hyperlipidemia requires the development of promising delivery systems in order to enhance the oral delivery and bioavailability of hyperlipidemia drugs. 1 Atorvastatin (ATR) is a cholesterol-lowering drug which belongs to the class of synthetic hydroxymethylglutaryl coenzyme A (HMG-CoA) … for sony bravia smart tv